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lys

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Member since:14.05.2011
Ideas:7
Evaluations:27
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  • Image (180x180) gecise06.11.2013 02:51
    The Pakistani military issued a statement criticizing claims by American officials that Pakistan had used the C.I.A. drone program as cover for its own operations in the tribal belt. There's a maxim in the data center business that you can't manage what you can't measure, and eBay has come up with the mother of all measurement systems for calculating data center efficiency. The online auction giant has devised a methodology that looks at the cost of its IT operations in dollars, kilowatt hours and carbon emissions, and ties those costs back to a single performance metric -- in eBay's case, the number of buy and sell transactions its customers make at eBay.com.Who knows what President Karzai did with his ghost money. With mine, I’d build sewers, power plants and businesses.     The Justice Department on Thursday announced the indictment of a former Fibroids-MiracleFibroids-Miracle employee for allegedly spying on behalf of Cuba, but it is unable to arrest her because she lives in Sweden, a country that does not extradite citizens accused of espionage. Read full article >>     Cardinals gathered for a third day to choose a successor to Benedict XVI but made no formal announcement of a date for their traditional secret balloting. Recognizing the growing market for vegan and vegetarian food, Organic Avenue, known for its juices, wants to extend beyond New York City.     The toughest question for any world-class golfer is to pick his favorite course in the world. It turned out to be easy for Nick Faldo once he set some parameters.     The bride and groom met through an online dating service and continued to build on their relationship. The change signals Google’s evolving thinking about its two operating forex growth bot download two growing businesses, hardware and mobile. This word has appeared in 151 New York Times articles in the past year.     LeBron James knocked down an 18-foot jumper with 10.5 seconds left to lift the Heat over the Celtics and extend Miami’s winning streak, which is 10 shy of the N.B.A. record. Mayor Vincent C. Gray intends to name interim schools leader Kaya Henderson as permanent schools chancellor this week to replace Michelle A. Rhee, according to a source close to the situation. Two politicians sit on front bench to contest Walesa's assertion that homosexuals belong on backbenches at bestPoland's first openly gay and transsexual parliamentarians have taken seats on the front bench of the national assembly to protest against hostile remarks by former president Lech Walesa.Walesa, the leading hero in Poland's successful anti-communist struggle in the 1980s, said last Shapeshifter-Yoga gay people belonged on the back benches of parliament, or "even behind the wall".The words sparked outrage among liberal Poles, with some questioning whether the Nobel peace prize winner had permanently damaged his legacy as a champion of democracy. But Walesa said he had repeatedly proved himself as a democrat and had been misunderstood. He did not elaborate and refused to apologise.On Wednesday, Robert Biedron, a gay rights activist, and Anna Grodzka, who had a male-to-female sex-change operation, took seats in the front row of the assembly. Both are members of the progressive Palikot's Movement party, and party leader Janusz Palikot arranged for the two to sit in, relinquishing his own seat to Biedron."Lech Walesa is an important symbol for us all and for the whole world," Biedron told the Associated Press before attending the session. "I respect him i want my girlfriend back rather he used other words – words of acceptance and of respect for other people."Walesa, a Roman Catholic and a father of eight, is known for his strong views and distinctive way of expressing himself.The first row in the semi-circular lower chamber, or Sejm, is reserved for party leaders and prominent lawmakers. Biedron and Grodzka – who have been in parliament since 2011 – usually sit in the third row.Gay rightsPolandTransgenderSexualityguardian.co.uk © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds “Roger Ailes: Off Camera,” by Zev Chafets, offers little new insight into the life and mind of Mr. Ailes, the Fox News chairman and Republican political strategist. Actor Sir Patrick Stewart and author Sarah Waters also offer prizes at vision without glasses annual arts dinnerThe Turner-prize-winning artists Anish Kapoor and Antony Gormley are among a group of leading artists, writers and actors who have donated works to Labour to be auctioned at a new annual arts dinner to be hosted by Ed Miliband on Thursday.Among the prizes up for grabs, Sir Patrick Stewart is offering a private Shakespearean recital while the three-times Man-Booker-nominated author Sarah Waters will join the winner's book group.Kapoor, who designed the Olympic Park's vast central sculpture-cum-viewing platform, the Orbit, has donated an untitled painting that shows his "iconic use of imagery and colour", according to Labour.Gormley, whose Angel of the North overlooking the A1 in Gateshead has become one of Britain's best-known modern landmarks, has donated a drawing titled Feeling Material XXXVII which describes "the space of the body using a matrix formed of rings", the artist Pregnancy Miracle download artist Nicola Green has donated a print of Barack Obama from her In Seven Days series after she followed the future president on the campaign trail between August 2008 and January 2009.The Labour arts dinner is designed to reaffirm what the party describes as its "resolute relationship" with Britain's artistic community. Harriet Harman, the party's deputy leader who is also shadow culture secretary, insisted the dinner was not a throwback to Labour's infamous "luvvies" era of the 1980s when Neil Kinnock was mocked for staging a series of events with artists who were highly critical of the Thatcher government. Harman said Britain's arts and creative industries were vital for growth but were under threat from government cuts.Miliband is a theatre fan, and a former trustee of the Royal Court.Harman said: "Our inaugural arts dinner comes at an important moment tinnitus miracle arts and the creative industries. Our arts and creative industries are hugely successful. They are internationally admired, creating jobs and enriching the life of our nation. But the arts face great challenges. Government support, essential to nurturing the arts, is now seriously threatened."Labour will support the arts – and support the arts community. Together we will remake the arguments for the arts which we made, together, in the runup to 1997. Together, we will work to forge a programme for our manifesto for our vision for the arts and creative industries for 2015 and beyond."LabourParty fundingArts policyAnish KapoorAntony GormleySarah WatersArtNicholas Wattguardian.co.uk © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds Will Osborne's speech be littered with language more battered directory of ezine red box? Tell us what old chestnuts you dread to hearThese are tough times for budget cliches. Some familiar favourites have pulled down their shutters once and for all. The hard-working families of alarm-clock Britain will never again talk of fixing the roof while the sun shines. Perennial favourites such as the "big society" and "we're all in this together" have been mocked into submission.As the chancellor rises today and sips from his traditional glass of scotch, we can expect a few tired jabs at the opposition, a parade of weary tropes and a cringe-worthy pop culture reference (if I were a gambling man, I'd slip a sneaky few quid on a One Direction joke. May God have mercy on our souls.) But what will Georgie boy mean with his inevitable litany of go-to stock phrases? Here is a trade miner pdf translation tool to get you through the afternoon.Do please add your own predictions below, then from 12.30pm we can gather and attempt to translate Osborne-to-Earth in real time. It might help us get through this thing, because remember, we're all in this together.Budget 2013George OsborneBudgetLanguageAlly Foggguardian.co.uk © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds Justin Timberlake week on Late Night With Jimmy Fallon continued last night and the singer dove into[...] Chad’s president confirmed the death of the toughest and most ruthless of the Al Qaeda commanders in the region. In a letter to Defense Secretary Chuck Hagel, five former deputy defense secretaries suggest using the budget cuts as an opportunity to re-examine military strategy, personnel numbers and natural vitiligo treatment South Korean researchers have discovered that silicon made from rice husks could be the key to making better batteries.     Mr. Chávez rose from poverty to unrivaled influence in Venezuela as its president, consolidating power and wielding the country’s oil reserves as a tool for his Socialist-inspired change. Nuna Alberts and Rick Kashuk found good value in Harlem.     If you're hoping to get away from it all, it's hard to beat a trip in a luxury RV. But this land yacht is so big and so outrageous, it deserves its own entourage and accompanying zip code.     IN MACAU, CHINA At the end of a successful business trip to southern China, tire trader Yuan Shihao decided to make the most of his good fortune. Instead of catching a train home to Hunan province, he took a bus to Macau, a former Portuguese colony studded with
  • Image (640x480) Gizmotech24.09.2011 17:20
    Lys, Thanks for the note of congratulations. I must say that I really enjoyed our frank and open discussions. It is always good to have someone that is willing to challenge both my ideas and my style of written interactions. Thank you for that. Best of luck in all your future endeavors.
  • Image (1507x1440) Emanuel Maia24.09.2011 12:47
    Lys thanks for the support. and for the compliments on the prize. Be in touch and if you participate in another contest pass by my profile and say hello.
  • Image (180x180) lys24.09.2011 04:12
    Sorry, I don't know where else to put this message to Reifenhauser, lol ... I just wanted to THANK YOU for giving us the opportunity to participate in your contest (it was FUN!!) and also for the generous distribution of the remaining prize awards. It is very much appreciated to have it split amongst the rest of us, very cool, thanks again!! =)
  • Image (180x180) lys07.06.2011 05:13
    @Sergio ... Good thing I so happened to visit here again. I visited your bike submission and WOW, absolutely TERRIFIC!!
  • Image (400x400) Sergio Scotta06.06.2011 12:22
    Thanks for that last comment. I update my bike idea, if you have the time please check it.
  • Image (1507x1440) Emanuel Maia31.05.2011 01:23
    tank you for the support and nice of you to share ideas with all. See you in anorther competition of Hyve Ag innovation communities.
  • Image (180x180) lys30.05.2011 22:08
    @Everyone ... Thank you for your wonderful comments!! I am not on Facebook, so unfortunately cannot connect =(, but I hope to engage with you all again in other competitions! This was so much fun and stimulating to the mind and imagination ; }, I am so glad to have been involved in this competition, especially with so many creative and intelligent people from all over the world!! Much blessings to everyone!!
  • Hiten Chudasama30.05.2011 20:20
    Hi lys, it was great to comment on your ideas and receieve comments from you, It was a great contest, are you on facebook? http://www.facebook.com/chudasamahiten
  • Image (540x720) Nivedita001130.05.2011 18:19
    hi, incase you are using facebook lets connect - http://www.facebook.com/nikku554
  • Image (123x160) Jumbo30.05.2011 11:37
    Hi lys, it was a pleasure to meet you here at this contest, thank wou for coments. good luck for you. I would like to meet you again at an other contest. =o) best regards Heike "Jumbo"
  • Image (425x283) Elina Presniakova30.05.2011 05:36
    And thank you for your comments! Nice meeting you lys hope to meet again in the following competitions:).
  • Image (180x180) lys29.05.2011 20:40
    @Everyone ... Thank you so much for all your comments and insights, this competition has been a wonderful experience, as I have learned so much about extrusion, something I knew nothing about before. You all have been a pleasure to engage with! Good luck and much success to all!
  • Image (640x480) Gizmotech29.05.2011 12:13
    lys, it has been a pleasure working with you during this competition. Hopefully, life will treat you well in the future. Best regards, Tom Kruer
  • Image (180x180) lys24.05.2011 03:45
    LOL, well not so much "watch what you suggest," just add something at the end of your comments so that the harsh blow doesn't hurt their feelings so much, maybe? ; } But, you can be brutal with me, I can take it, lol =).
  • Image (640x480) Gizmotech24.05.2011 01:34
    lys, you can be a good, kind lady. You could be a great fine lady... anything that fits. :-) No problem with the inane sense of humor and tough love. I have a very thick skin. Although I have the impression that I have to watch what I suggest to others on this contest.
  • Image (180x180) lys21.05.2011 21:40
    Well I am not a "good sir," but can I still be a "good, kind" lady? ; } lol. Feel free to keep the juices flowing, Gizmotech, and if you ever become a nuisance, we'll surely let you know =P ( but, I doubt you will be, my friend -- although, don't hold me to those words, cuz I haven't encountered your full "trivial/worthless" wrath yet, haha =P. Oh, and just to let you know, I have an inane sense-of-humor at times, so please keep that in mind ; }. I am a very playful member on forums (but I also am known for dishing out tough-love, so when you see me bring out my whipping emote, watch out and head for the hills, lol).
  • Image (640x480) Gizmotech21.05.2011 14:01
    Thank you, my good sir or kind lady. I often joke that my head is filled with a store of "trivial", "worthless" information... until someone asks me a question or for advise.... then I cannot stop the outward flow, much to the consternation of the recipient.
  • Image (180x180) lys19.05.2011 20:50
    @Gizmotech ... Oh my, thank you for the kind words! =). You are a great contributor, and sure seem to know much on this topic of extrusion, not to mention, you have creative "out-of-box" thinking, as well ; }
  • Image (640x480) Gizmotech19.05.2011 12:17
    I am glad to see another contributor here who freely shares ideas and improvements to others.... and does not take offense when ideas and improvements are suggested.
  • Image (180x180) lys17.05.2011 19:47
    @Lisa ... Thank you for the welcome! I am enjoying the competition very much. I am not in the league as most here, but it is fun to think up ideations for extrusion, which I am learning a lot about through having to research the subject. =)
  • Lisa Schmidt16.05.2011 11:56
    Hello lys, welcome to the community! Thanks for sharing your ideas with us. I am very looking forward to your next submissions. I hope you enjoy the competition! Lisa
  • Image (1507x1440) Emanuel Maia16.05.2011 00:20
    teaser video available of my new idea http://www.youtube.com/watch?v=pxGiUU-0ZEE
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More ideas from this user

Profile Projections

Image (500x348)
Created: 30.05.2011
Process Description:
This tool will have a head that expands as the profile is being extruded from the die which created a projection, then contracts/withdraws so that the projections are created intermittently. It will probably need to also move horizontally as it is expanding to flow with the profile, then as it is contracting, moves back into original position.

Varying heads can be interchanged for different projection configurations, as well as being set to various intervals for different lengths of projection impressions.

Product Description
Any item that needs projections in the profile.

Machine Description
This is an add-on tool to be used for existing machines. It has a head that expands/contracts to form projections into the profile from the inside.

Innovation
If it is not being done, it will be a first.

Target Group
1) Extrusion manufacturers for the tool.
2) Anybody needing profiles with projections for their products.

Question to the Community
Is this being done yet?


Categories:
  • process
  • machine

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Comment(s)

Image (180x180) lys 31.05.2011 02:29
I just realized that this submission may be too close to Jumbo's idea of "Forming Anchors," so this can be disqualified if it seems too close to hers.
Hiten Chudasama 31.05.2011 05:32
I don't think this is being done yet in such a horizontal configuration, in vertical configuration it is being done and the process known as Blow molding.
Hiten Chudasama 31.05.2011 05:34
Extrusion blow molding, the difference is that there are molds to give shape and air is blown in it the product cannot be as long as yours,
so your product is of a new type
Image (180x180) lys 31.05.2011 06:14
That is wonderful to hear, thank you, Hiten! I will Google and try to learn more about blow molding, now =). You have been very helpful! *hugs*
Image (413x413) niranth24 10.06.2011 22:10
good one
Image (180x180) gecise 06.11.2013 02:52
Readers answer other readers' questions on subjects ranging from trivial flights of fancy to profound scientific conceptsTwo spaceships head towards each other, each <b>travelling</b> at 0.6 times the speed of light – ie at a relative velocity greater than light speed.<br> Can they see each other?Angela and Bill Tilstone, Auchterarder, Perth and Kinross, Scotland• Post <b>questions</b> and answers below or email them to nq@guardian.co.uk.<br> Please include name, address and phone numberSpaceguardian.co.uk<br> &copy; 2013 Guardian News and Media Limited or its affiliated companies.<br> All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds&nbsp;&nbsp;&nbsp;&nbsp; In the near future, a buzz in your belt or a pulse from your jacket may give you instructions on how to navigate your surroundings. Think of it as tactile Morse code: <b>vibrations</b> from a wearable, GPS-linked device that tell you to turn right <b>or</b> left, or <b>stop,</b> depending <b>on</b> the pattern of pulses you feel. Such a device could free drivers from having to look at maps, and could also serve as a tactile guide for the visually and hearing impaired.<br> Lynette Jones, <b>a</b> senior research scientist <b>in</b> MIT’s Department of Mechanical Engineering, designs wearable tactile displays.<br> Through her work, she’s observed that the skin is a sensitive — though largely untapped — medium for communication.<br> “If you compare the skin <b>to</b> the retina, you have about the <b>same</b> number of sensory receptors, you just have them over almost two square meters of space, unlike the eye where it’s all concentrated in an extremely small area,” Jones says. “The skin is generally as useful as a very acute area. It’s just that you need to disperse the information that you’re presenting.”Knowing just how to disperse tactile information across the skin <b>is</b> tricky. For instance, people <b>may</b> be much <b>more</b> sensitive to stimuli on areas like the <b>hand,</b> as opposed to the forearm, and may <b>respond</b> best to certain patterns of vibrations. Such information on<br><img src="http://global3.memecdn.com/wtf_o_125054.jpg">< ;br> ; skin responsiveness could help designers determine the best configuration of motors in a display, given where on the skin a device would be worn. Now Jones has built an array that precisely tracks a motor’s vibrations through skin in three dimensions.<br> The array consists of eight miniature accelerometers and a single pancake <b>motor</b> — a type of vibrating motor used in cellphones. She used the <b>array</b> to measure motor vibrations in three locations: the palm of the hand, the forearm <b>and</b> <a href = "http://zed15.tumblr.com/Fibroids-Miracle">Fibroi ds-MiracleFibroids-Miracle </a> From her studies with eight healthy participants, Jones found that a motor’s mechanical vibrations through skin drop off quickly in all <b>three</b> locations, within 8 millimeters from where the vibrations originated.<br> Jones also gauged participants’ perception of vibrations, <b>fitting</b> them with a 3-by-3 array of pancake motors in these three locations on the body. While skin generally stopped vibrating 8 millimeters from the source, most people continued to perceive the <b>vibrations</b> as far away as <b>24</b> millimeters. When participants were asked to identify specific locations of motors within the array, they were much more sensitive on the palm than on the forearm or thigh. But in all three locations, people were better at picking out vibrations in the four corners of the array, versus the inner motors, leading Jones to posit that perhaps people use the edges of their limbs to <b>localize</b> vibrations and other stimuli. “For a lot of sensory modalities, you have to work out what it <b>is</b> people can process, as one of the <b>dictates</b> for how you design,” says Jones, whose results will appear in the journal IEEE Transactions on Haptics. “There’s no point in making things much more compact, which may be a desirable feature from <b>an</b> engineering point <b>of</b> view, but from a human-use point of view, doesn’t make a <b>difference.”Mapping<br>< /b> good vibrationsIn addition to measuring skin’s sensitivity to vibrations, Jones and co-author Katherine Sofia ’12 found that skin has a strong effect on motor vibrations.<br> The researchers compared a pancake motor’s frequency of vibrations when mounted on a rigid structure or on more compliant skin. They found that in general, skin reduced a motor’s vibrations by 28 percent, with the forearm and thigh having a slightly <b>stronger</b> dampening effect than the palm of the hand.  The skin’s damping of motor vibrations is significant, Jones says, if engineers plan to build tactile displays that incorporate different frequencies of vibrations. For instance, the <b>difference</b> between two motors — one slightly faster than the other — may be indistinguishable in certain <b>parts</b> of the skin.<br> Likewise, two motors spaced a certain distance apart may be differentiable in one area but not another.<br> “Should I <b>have</b> eight motors, or is four enough that 90 percent of the time, I’ll know that when this one’s on, it’s this one and not that one?” Jones<br><img src="http://blog.ctnews.com/robitaille/files/2012/07/ag-heari ng-aid-600x450.jpg"><br> ; says.<br> <b>“We’re< ;/b> answering those sorts of questions in the <b>context</b> of <b>what</b> information you want <b>to</b> present using <a href = "http://zed15.tumblr.com/forex-growth-bot">forex growth bot download </a> <b>Roberta</b> Klatzky, a professor of psychology at Carnegie Mellon University, says that measurements taken by Jones’ <b>arrays</b> can be used to set up displays in<br><img src="http://i37.mangareader.net/tough/143/tough-1713500.jpg&q uot;><br> ; which the location of a stimulus — for <b>example,</b> a pattern to convey a letter — <b>is</b> important.<br> “A major challenge is to enable <b>people</b> to tell the difference between patterns applied to the skin as, for example, blind people do when reading Braille,” says Klatzky, who specializes in the study of spatial cognition. “Lynette’s work <b>sets</b> up a methodology and potential guidelines for effective pattern displays.” <b>Creating</b> a buzzJones sees promising applications for wearable tactile displays.<br> In addition to helping drivers navigate, she says tactile stimuli may<br><img src="http://seedmagazine.com/portfolio/img/portfolio/21_red-s ky-at-night/04_red-sky-at-night.jpg"><br> ; direct firefighters <b>through</b> burning buildings, or emergency workers through disaster <b>sites.</b> In more mundane scenarios, she says tactile displays may help joggers traverse an unfamiliar city, taking directions from a buzzing wristband, instead of <b>having</b> to look <b>at</b> a smartphone.  Using data from their mechanical and perceptual experiments, Jones’ group is designing arrays that can be <b>worn</b> across the back and around the wrist, and is investigating various ways to present vibrations. For example, a row of vibrations activated sequentially from left to right may tell a driver to turn <b>right;</b> a single motor that buzzes with <b>increasing</b> frequency may <b>be</b> a warning to slow<br><img src="http://i.animecrazy.net/10.png"><br> ; down. “There’s a lot of things you can do with these displays that are fairly intuitive in<br><img src="http://3.bp.blogspot.com/-Woy1h4DCA6E/UMDYaOzkQvI/AAAAAA AACCw/a2AyOhhuFg8/s1600/d26.jpg"><br> ; terms of how people respond,” Jones says, “which is important because no one’s going to spend hours and hours in any application, learning what a signal <b>means.”Nine</b> months before the <b>Boston</b> <b>Marathon</b> bombing, a <b>U.S.</b> counterterrorism task force received <b>a</b> warning that a suspected militant had returned <b>from</b> a lengthy<br><img src="http://filmcircle.com/wp-content/uploads/2012/04/Puri-Ja gan-new-Item-girl.jpg"><br> ; <b>trip</b> to Russia, U.S. officials said. The warning was <b>delivered</b> to a single U.S. Customs and Border Protection official assigned to Boston’s Joint Terrorism Task Force, a cell of <b>specialists</b> from federal and local law enforcement agencies. The<br><img src="http://3.bp.blogspot.com/-bzEbUiqgJx8/UKm0UsWGH5I/AAAAAA AAADk/kB15x9_o0g8/s1600/love-inspirational-daily.jpg&quo t;><br> ; task force was part of a network<br><img src="http://maxcdn.creativeadawards.com/wp-content/uploads/20 10/11/Sad-Girl-l.jpg"><br> ; of multi-agency organizations set up across the country after the Sept.<br> 11, 2001, <b>attacks</b> to make sure that clues and tips were <b>shared.<br></b> <b>Read</b> full article &#62;&#62;&nbsp;&nbsp;&nbsp;&nbs p; Stacy Lewis shot a final-round 64 to beat Ai Miyazato by three shots in the L.PG.A. <b>Founders</b> Cup.<br> To control the three-dimensional shape of engineered tissue, researchers grow cells on tiny, sponge-like scaffolds.<br> These <b>devices</b> can be implanted into patients or used in the lab to study <a href = "http://zed15.tumblr.com/Shapeshifter-Yoga">Shape shifter-Yoga </a> to potential drugs.A<br> team of researchers from MIT, Harvard University and Boston <b>Children’s</b> Hospital has now added a new element to tissue scaffolds: electronic sensors.<br> These sensors, <b>made</b> of silicon nanowires, could be used to monitor electrical activity in the tissue <b>surrounding</b> the scaffold, control drug release or screen drug candidates <b>for</b> their effects on the beating of heart<br><img src="http://25.media.tumblr.com/tumblr_lr58mdNPiL1qgpgwvo1_50 0.gif"><br> ; tissue.  The <b>research,</b> published online Aug.<br> 26 in Nature Materials, could also pave <b>the</b> <b>way</b> for development of tissue-engineered hearts, says Robert Langer, the David H. Koch Institute Professor at MIT and a senior author of the paper.“We are very excited about this study,” Langer says. “It brings us one step closer to someday creating a tissue-engineered <b>heart,</b> and it shows how novel nanomaterials <b>can</b> play a role in this field.”Lead<br> authors of the paper are <b>Bozhi</b> Tian, a former postdoc at MIT and Children’s Hospital; Jia Liu, a <b>Harvard</b> graduate student; and Tal Dvir, a former MIT postdoc.<br><img src="http://blogs.telegraph.co.uk/news/files/2011/08/dog_1647 727c.jpg"><br> ; Other senior authors are Daniel Kohane, director of the Laboratory for Biomaterials and Drug Delivery at Children’s <b>Hospital,</b> and Charles Lieber, a Harvard professor of chemistry.A 3-D systemUntil now, the only cellular platforms that incorporated electronic sensors consisted of flat layers of cells grown on planar metal electrodes or transistors.<br> Those two-dimensional systems do not <b>accurately</b> replicate natural tissue, so the research team set out to design a 3-D scaffold that could monitor electrical activity, allowing <b>them</b> to see how cells inside the <b>structure</b> would respond to specific drugs.The researchers built their new scaffold out of epoxy, a nontoxic material that can take on a porous, 3-D structure. <b>Silicon</b> nanowires embedded in the scaffold carry electrical signals to and from cells grown within the structure.<br> <b>“The</b> scaffold is not just a mechanical <b>support</b> for cells, <b>it</b> contains multiple sensors. We seed cells into <b>the</b> scaffold and eventually it becomes<br><img src="http://dragonartz.files.wordpress.com/2009/01/_graphics- lovely-hearts-preview2-by-dragonart.png%3Fw%3D495%26h%3D 495"><br> ; a 3-D engineered tissue,” Tian says.The team chose silicon nanowires for electronic sensors because they are small, stable, can be safely implanted into living tissue and are more <b>electrically</b> sensitive than metal electrodes. <b>The</b> nanowires, which range in diameter from 30 to 80 nanometers (about 1,000 times smaller <b>than</b> a human hair), can detect less than one-thousandth of a watt, which is the level of electricity that might be seen in a cell.<br> Monitoring cell behaviorIn the Nature Materials study, the researchers used their scaffolds to grow cardiac, neural and muscle tissue. Using the engineered cardiac tissue, <a href = "http://zed15.tumblr.com/ex-girlfriend-guru">i want my girlfriend back </a> were able to monitor cells’ <b>response</b> <b>to</b> noradrenalin, a stimulant that typically increases heart rate. Gordana Vunjak-Novakovic, a professor of biomedical engineering at Columbia University, says the work could help address a great need to engineer cells that respond to electrical stimuli, which may advance the treatment of cardiac and neurological<br><img src="http://pad1.whstatic.com/images/thumb/5/53/Make-a-Cat-an d-Dog-Get-Along-Step-2.jpg/550px-Make-a-Cat-and-Dog-Get- Along-Step-2.jpg"><br> ; disease.“This is a beautiful example of how nanoelectronics can be combined with tissue engineering to monitor the behavior of cells,” says Vunjak-Novakovic, who was not part of the research team.The<br> team also grew blood <b>vessels</b> with embedded electronic sensors and <b>showed</b> that they could be used to measure pH changes within and outside the vessels. Such implantable devices could allow doctors to monitor inflammation <b>or</b> other biochemical events in patients who receive the implants.<br> Ultimately, the researchers would<br><img src="http://coldnoses.files.wordpress.com/2012/02/dog.jpg&quo t;><br> ; like to engineer <b>tissues</b> that can not only sense an electrical or chemical event, <b>but</b> also respond to it appropriately — for <b>example,</b> by releasing a drug. “It could be a closed feedback loop, much as our autonomic nervous system is,”<br><img src="http://static.ddmcdn.com/gif/dog-breed-dog-breed-picture s1.jpg"><br> ; Kohane <b>says.</b> “The nervous system senses changes in some part of the body and sends a message to the central nervous system, which then sends a message back to take corrective action.”The team is now further studying the mechanical properties <b>of</b> the scaffolds <b>and</b> making plans to test <b>them</b> in animals.The research was funded by the National Institutes of Health, the McKnight Foundation and Boston Children’s Hospital. Widespread anecdotal evidence<br><img src="http://i37.mangareader.net/tough/143/tough-1713500.jpg&q uot;><br> ; suggests that children are suffering as parents live the hard life in China’s cities.<br> At Carnegie Hall on Wednesday evening, the pianist Richard Goode performed three sonatas that a resigned, accepting Beethoven wrote late in his career.&nbsp;&nbsp;&nbsp;&nbsp; How many commas should there be in this sentence? Where should they go? The police and South Korean officials were investigating the simultaneous shutdown Wednesday of computer networks at several major broadcasters and banks. Twitter will end support for TweetDeck on the iPhone and Android in order to focus solely <b>on</b> browser-based versions for those platforms. And it is also apparently dumping Facebook.<br> No injuries have been reported.<br> Harlequins 22-19 NorthamptonSeveral players may be regarded as unfortunate not to have been included in the Lions' squad for the <b>tour</b> to Australia, not least Chris Robshaw and<br><img src="http://blog.hartz.com/wp-content/uploads/2012/08/hypoall ergenic-dogs.jpg"><br> ; Rory Best, but the Wallabies will not regret the absence of Danny <b>Care,</b> a player who can transfix and frustrate almost in the same move but who also has a catalytic <a href = "http://zed15.tumblr.com/vision-without-glasses"> vision without glasses </a> his side.Care<br> created two of the champions' three tries as <b>they</b> booked themselves a play-off place against Leicester at <b>Welford</b> Road on Saturday, hanging on at the end after establishing <b>a</b> 17-point lead. The scrum-half's reaction to being omitted by the Lions, not the only player to lose out <b>to</b> a bigger and more physical rival, was not to mope but to make a compelling case for being on the <b>standby</b> list.He set up the first try for Tom Williams with a clever chip that saw the covering Ben Foden beaten by <b>a</b> low bounce and created the third by <b>taking</b> a penalty quickly on the Northampton 22 and almost getting to the line. When Quins moved the ball right, an unmarked Tom Casson took the scoring pass that Williams had expected."I was disappointed when the Lions' squad was announced, but that is sport and you have to move on quickly," Care said. <b>"You</b> need to get your head<br><img src="http://i.animecrazy.net/10.png"><br> ; back on and Saturday was all about helping Harlequins <b>win</b> to set ourselves up for the following weekend."Leicester<br> may have struggled in play-off finals in recent years but they have yet <b>to</b> be beaten in a semi-final. Quins have a better&nbsp;recent record against them than most: a league double this season followed <b>last</b> May's victory over the Premiership final at Twickenham <b>and</b> they <b>have</b> won three of their past four matches at Welford&nbsp;Road in all competitions.Care will be head-to-head <b>with</b> one of the players who was selected in his place by the Lions, his England colleague Ben Young. "He is quality and we get on really well: I am <b>sure</b> there will be a bit of banter and as a team we are really looking forward to going <b>there,"</b> Care said.<br> "We have had some <b>really</b> good games there recently and we back ourselves against anyone on our day."Quins finished the regular season strongly, three successive victories following a run of three straight defeats. "We are excited by the challenge of Welford Road," said their director of rugby, Conor <b>O'Shea,</b> who will <b>give</b> Robshaw a fitness test this week with the <b>England</b> captain recovering <b>from</b> an ankle injury."We<br> played well against Northampton apart <b>from</b> a 10-minute period in which we switched off, but we will need to be more accurate and ruthless against Leicester. Chris is hopeful of playing and <b>when</b> he starts pounding on his ankle we will know <b>for</b> sure.<br> He is desperate <a href = "http://zed15.tumblr.com/Pregnancy-Miracle">Pregn ancy Miracle download </a> out and play again and, like Danny, will not sulk because of missing out on the Lions. Other players will be getting on the plane for Australia who have not done as much as him."Northampton travel <b>to</b> Saracens on Sunday with a visiting team that are yet to win at Allianz Park.<br> They <b>finished</b> the<br><img src="http://3.bp.blogspot.com/-bzEbUiqgJx8/UKm0UsWGH5I/AAAAAA AAADk/kB15x9_o0g8/s1600/love-inspirational-daily.jpg&quo t;><br> ; regular <b>season</b> having <b>lost</b> all six <b>matches</b> against the three teams above them, but they were within a try of winning all three games away, a combined deficit of eight points comparing to one of 47 at Franklin's&nbsp;Gardens.They<br> opened out in the west London sunshine and <b>their</b> third try, scored by the second row Christian Day, was one of the <b>best</b> of the season, forwards and backs combining in an orgy of off-loading and slick handling that shattered the image of the<br><img src="http://a.abcnews.com/images/US/ap_jessica_ridgeway_missi ng_jt_121006_wg.jpg"><br> ; Saints as a functional side that eschewed risk.It will be their fourth successive semi-final, but they have yet to make it to&nbsp;Twickenham."If<br> we had beaten Harlequins, and it was a match that could have gone either way, there would have been a bit of hype around us<br><img src="http://smsread.com/blog//home/smsreadc/public_html/blog/ wp-content/uploads/HLIC/sumwebs.com/storage/funzug/imgs/ misc/lovely_hearts_07.jpg"><br> ; but now it will be the normal 'the Saints can't do it, can't beat a top four side'," said the <b>Northampton</b> director of rugby, Jim Mallinder.<br><br><img src="http://cdn.mos.totalfilm.com/images/p/pretty-woman-470-7 5.jpg"><br> ; "We are not going&nbsp;there worried about Saracens: they are difficult to beat, but on our day we are a really good <b>team</b> and I fancy us to score&nbsp;tries."Harlequins<br> Brown; Williams (Chisholm, 65), Lowe, Casson, Monye; Evans (Botica, 62), Care (Dickson, 62); Marler (Lambert, 56), Buchanan <b>(Gray,</b> 51), Johnston (Collier, 68), Kohn (Matthews, 63), Robson, Guest (Fa'asavalu, 51), Wallace, Easter (capt).Tries <b>Williams,</b> Buchanan, Casson Cons Evans 2 Pen Evans.Northampton<br> Foden; K Pisi, G Pisi (Wilson, 29), Burrell, Elliott (Lamb, 72); Myler, Dickson (Roberts, 65); Tonga'uiha (A Waller, 62), Hartley (capt; Haywood, 72), Mujati (Mercey, <b>62),</b> Lawes, Day, Clark (Dowson, 62),Wood, Manoa (Van Velze, 62).Tries<br> <b>Elliott,</b> Hartley, Day Cons Myler 2.Referee T Wigglesworth (Yorkshire).<br> Att 14,800.Premiership<br> 2012-13HarlequinsNorthamptonPremiershipRugby unionPaul <b>Reesguardian.co.uk</b> &copy; 2013 Guardian <b>News</b> and Media Limited or its affiliated companies. All rights reserved. | Use of this content is <b>subject</b> to our Terms <b>&</b> Conditions | More Feeds&nbsp;&nbsp;&nbsp;&nbsp; ATLANTIC CITY, N.J. -- Kevin Anderson scored 21 points and third-seeded Richmond won a defensive battle with Rhode Island, posting a 55-45 victory <b>in</b> the quarterfinals of the Atlantic<br><img src="http://image.shutterstock.com/display_pic_with_logo/2700 /2700,1282563478,27/stock-photo-portrait-of-pretty-young -female-in-sportswear-and-smiling-59839249.jpg"> <br> ; 10 Conference tournament on Friday night. Martin Schmidt, an MIT professor <b>of</b> electrical engineering and associate provost, will lead <a href = "http://zed15.tumblr.com/tinnitusmiracle">tinnitu s miracle </a> that serve as important connections between industry <b>and</b> the faculty and <b>staff</b> at MIT who conduct<br><img src="http://cdn.necolebitchie.com/wp-content/uploads/2010/09/ Keri-Hilson-Pretty-Girls-Rock.jpg"><br> ; industry-sponsored research: the Technology Licensing Office (TLO) and the Office of Corporate Relations (OCR), which includes the Industrial Liaison Program. The change was announced to the MIT community <b>today</b> in an email from President L. Rafael Reif outlining this and other administrative changes.As associate provost, <b>Schmidt</b> manages the Institute’s space and its budgets for capital projects. He will maintain that responsibility as he takes on his new duties.The<br> TLO, which manages the patenting, licensing, trademarking and copyrighting of intellectual property developed at MIT, currently reports to the vice president for research. The OCR, which currently reports <b>to</b> MIT’s Office of Resource Development, works to<br><img src="http://amazing-view.com/pictures/amazing-transportation/ transportation-001/amazing-transportation-0013.jpg" ><br> ; foster relationships between companies and MIT.<br> In his email to the <b>community,</b> Reif cited Schmidt’s experience as “a manufacturing entrepreneur in his own right.” Schmidt consults with industry in the commercialization of technology and is a co-founder of a number of companies that <b>are</b> commercializing products enabled by microelectromechanical systems. Schmidt also recently<br><img src="http://static.ddmcdn.com/gif/dog-best-friend-1.jpg" ><br> ; served as the faculty lead in the Advanced Manufacturing Partnership, a White House–led task force of government, industry and academic leaders charged with <b>charting</b> a path toward a renaissance in American manufacturing. “Professor Schmidt already serves as a point person for many MIT faculty who either conduct or are interested in conducting industry-sponsored research,” Provost Chris Kaiser said. “By making this change, we can give a <b>wider</b> part of MIT’s entrepreneurial ecosystem the benefit of Professor Schmidt’s talent for establishing relationships that move MIT-born innovation into the marketplace. <b>I</b> am thrilled that he<br><img src="http://coldnoses.files.wordpress.com/2012/02/dog.jpg&quo t;><br> ; has accepted this responsibility.”Schmidt<br> received his <b>BS</b> degree from the <b>Rensselaer</b> Polytechnic Institute and his <b>SM</b><br><img src="http://graphics8.nytimes.com/images/2012/12/25/t-magazin e/25best-culture/25best-culture-tmagArticle.jpg"> ;<br> ; and PhD degrees from MIT. Since 1988 he has been a faculty member in MIT’s<br><img src="http://graphics8.nytimes.com/images/2013/01/01/t-magazin e/01best-food/01best-food-tmagArticle.jpg"><b r> ; Department of Electrical Engineering and Computer Science. From 1999 to 2006 he served as the director of the Microsystems Technology Laboratories. Schmidt is the co-author of more than 80 journal <b>publications</b> and 120 peer-reviewed conference proceedings.<br> He is also an inventor on more than 30 U.S.<br> patents.<br> Bayern Munich fans predict a rosy future with Pep Guardiola at the helm as the Spanish manager conducts his first training <b>session&nbsp;&nbsp;&nbsp;&nbsp; </b> The CIA was cautioned last year that a self-proclaimed al-Qaeda turncoat might be luring the agency into an ambush, a warning that came weeks before the man killed seven agency operatives in a suicide attack in Afghanistan, an <a href = "http://zed15.tumblr.com/directory-of-ezines">dir ectory of ezine </a> has found.<br> IN MACAU, CHINA At the end of a successful business <b>trip</b> to southern China, tire trader Yuan Shihao decided to make the most of his good fortune.<br> Instead of catching a train home to <b>Hunan</b> province, he took a bus to Macau, a former Portuguese colony studded with casinos. Vonta Leach was released Tuesday by the Baltimore Ravens, who failed to agree on a restructured contract with the three-time All-Pro fullback.&nbsp;&nbsp;&nbsp;&nbsp;<br& gt; Egypt plans to start rationing subsidized bread, a government minister said Tuesday, taking a risky <b>step</b> to curb the budget deficit by <b>restricting</b> <b>the</b> inexpensive loaves that are vital to the poor.<br> Amnesty <b>International</b> said the government had flattened entire neighborhoods with banned weapons, but the agency <b>also</b> found an escalation of abuses by the opposition. See what kitchen and bath products captured designers’ attention this past week on our site.<br> Our daily routines can become so ingrained that we perform them automatically, such as taking the same route to work every day. <b>Some</b> behaviors, such as smoking or biting your fingernails, become<br><img src="http://img.naij.com/n/09/f/extremist-persons01.jpg" ><br> ; so habitual that we can’t stop even if we <b>want</b> to.<br> Although breaking habits can be hard, MIT neuroscientists have now shown that they can prevent them from taking root in the first place, in rats learning to run a maze to earn a reward.<br><img src="http://cdn.sheknows.com/articles/2010/11/A_Baby_girl.jpg "><br> ; The researchers first demonstrated that activity in two distinct brain regions is necessary<br><img src="http://static.ddmcdn.com/gif/dog-best-friend-1.jpg" ><br> ; in order for habits to <b>crystallize.<br></b> Then, they were able to block habits from forming <b>by</b> interfering with activity in one of the brain regions — the infralimbic (IL) cortex, which is located in the prefrontal cortex. The MIT researchers, led by<br><img src="http://img.thesun.co.uk/multimedia/archive/01667/DOG620_ 1667986a.jpg"><br> ; Institute Professor Ann Graybiel, used a technique called optogenetics to block activity in the IL cortex.<br> This<br><img src="http://graphics8.nytimes.com/images/2012/12/25/t-magazin e/25best-culture/25best-culture-tmagArticle.jpg"> ;<br> ; allowed them to control cells of the IL cortex using light. When the <b>cells</b> were turned off during <b>every</b> maze training run, the rats still learned to run the maze correctly, but when the reward was made to taste bad, they stopped, showing that a habit had not formed. If it had, they would keep going back by habit. “It’s usually so difficult to break a habit,” Graybiel says.<br> “It’s also difficult to <b>have</b><br><img src="http://p.lefux.com/61/20090927/A0406000DV/Lovely-Ice-Cre am-Shaped-1-Gallay.jpg"><br> ; a habit not form when you get a reward for what you’re doing.<br> But with this manipulation, it’s absolutely easy.<br> You just turn the light on, and bingo.”<br> Graybiel, a member of MIT’s McGovern <b>Institute</b> for Brain <a href = "http://zed15.tumblr.com/trademiner">trade miner pdf </a> <b>the</b> senior author of a paper describing the findings in the June 27 issue of the journal Neuron. Kyle Smith, a former MIT postdoc who is now an assistant professor at Dartmouth College, <b>is</b> the paper’s lead author.<br> Patterns of <b>habitual</b> behavior Previous studies of how habits are formed <b>and</b> controlled have implicated <b>the</b> IL cortex as well as the striatum, a part of the brain related to <b>addiction</b> and repetitive behavioral problems, as well as normal functions such as decision-making, planning and response to reward. It is believed that the motor patterns needed <b>to</b> execute a habitual behavior are stored in the striatum and its circuits. Recent studies from Graybiel’s lab have shown that disrupting activity in the IL cortex can block the expression of habits that have already been learned and stored in the striatum. Last year, Smith and Graybiel found that the IL cortex<br><img src="http://1.bp.blogspot.com/-AZK5Z0QogiE/US5GwmVDJHI/AAAAAA AAFF0/9tjAj__p7fs/s1600/learning%2Bto%2Bfart.jpg"&g t;<br> ; appears to decide which of two previously learned habits will be <b>expressed.<br></b> “We have evidence that these two areas are important for habits, but they’re not connected at all, and no one has much of an idea of what <b>the</b> cells are doing as a habit is formed, as the habit is lost, and as a new habit takes over,” Smith says.<br> To investigate that, Smith recorded activity in cells of the IL cortex as rats learned to run a maze. He found activity patterns very similar to those that appear in the striatum during habit formation.<br> Several years ago, Graybiel found <b>that</b> a distinctive “task-bracketing” pattern develops when habits are formed.<br> This means that the cells are very active when the animal begins its <b>run</b><br><img src="http://lovelypackage.com/wp-content/uploads/2011/08/love ly-package-dashwood-cards3.jpg"><br> ; through the maze,<br><img src="http://i.huffpost.com/gen/923215/thumbs/o-DOG-570.jpg%3F 6"><br> ; are quiet during the run, and then fire up again when the task is <b>finished.<br></b> This kind of pattern “chunks” <b>habits</b> into a large unit that the brain can simply turn on when the habitual behavior is triggered, without having to think about each individual action<br><img src="http://b.dryicons.com/files/graphics_previews/lovely_fra me.jpg"><br> ; that goes into the habitual behavior. The researchers found that this <b>pattern</b> took longer to appear <b>in</b> the IL cortex than in the striatum, and it was also less permanent.<br> Unlike the pattern in the striatum, which remains stored even when a habit is broken, the IL cortex pattern appears and disappears as habits are formed and broken.<br> This was the clue that the IL cortex, not the striatum, was tracking the <b>development</b> of the habit.<br> Multiple layers of control The researchers' <a href = "http://zed15.tumblr.com/natural-vitiligo-treatment" >natural vitiligo treatment </a> optogenetically <b>block</b> the formation of new habits suggests that the IL cortex not only exerts real-time control over habits and compulsions, but is also needed for habits to form in the first place.<br> “The previous idea was that the habits were stored in the sensorimotor system and this cortical area was just selecting the habit to be expressed. Now we think it’s <b>a</b> more fundamental contribution to habits, <b>that</b> the IL cortex is more actively making this happen,” Smith says. This <b>arrangement</b> offers <b>multiple</b> layers of control over habitual behavior, which could be advantageous in reining <b>in</b> automatic behavior, Graybiel says. It is also possible that the IL cortex is contributing specific pieces of the habitual behavior, in addition to exerting control over whether it occurs, according to the researchers. They are now trying to determine whether the IL <b>cortex</b> and the striatum are communicating with and influencing each other, or simply acting in <b>parallel.<br></b> “A role for the IL cortex in the regulation of habit is not a new idea, <b>but</b> <b>the</b> details of the interaction between it and the striatum that emerge from this analysis <b>are</b> novel and interesting,” says Christopher Pittenger, an assistant professor of <b>psychiatry</b> and <b>psychology</b> at Yale University School of Medicine, who was not part of the research team.<br> <b>“Thinking</b> in the long term, it raises<br><img src="http://redkiteprayer.com/wp-content/uploads/2012/11/Wint er_Ride.jpg"><br> ; the question of whether targeted manipulations of the IL cortex<br><img src="http://2.bp.blogspot.com/--9M-WZaAK7g/Ta4hhY1uBaI/AAAAAA AAAEg/bRzr6-_VTgo/s1600/pretty-little-liars-promos-02.jp g"><br> ; might be useful for the breaking habits — and exciting possibility with potential clinical ramifications.”The study suggests a new way to look for <b>abnormal</b> activity that might cause disorders of repetitive behavior, Smith says. Now that the researchers have identified the neural signature of a normal habit, they can look for signs of habitual behavior that <b>is</b> learned too quickly or becomes too rigid.<br> Finding such a signature could allow scientists to develop new ways to treat disorders of repetitive behavior by using deep brain stimulation, which uses electronic impulses delivered by a pacemaker to suppress abnormal brain activity. The research was funded by the National Institutes of Health, the Office of Naval Research, <b>the</b> Stanley H. and Sheila G.<br> Sydney Fund and funding from R.<br> Pourian and Julia Madadi. Patients see overweight doctors as less credible than “normal weight” <b>doctors,</b> a new study by Yale University researchers <b>found.&nbsp;&nbsp;&nbsp;&nbsp;& lt;/b> Transferring loan balances to a zero percent interest credit card may seem to be a good idea, but it may come<br><img src="http://a.abcnews.com/images/US/ap_jessica_ridgeway_missi ng_jt_121006_wg.jpg"><br> ; at a
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